Gene Therapy for Arthritis

Gene therapy for arthritis

Arthritis is among the leading causes of disability in the developed world. There remains no cure for this disease and the current treatments are only modestly effective at slowing the disease's progression and providing symptomatic relief. The clinical effectiveness of current treatment regimens has been limited by short half-lives of the drugs and the requirement for repeated systemic adminis...

Gene therapy for rheumatoid arthritis

Gene therapy for rheumatoid arthritis?

Gene therapy for arthritis: defining novel gene targets

Treatment of Traumatic Arthritis using Gene Therapy

Following a single intra-articular injection of an adenoviral vector capable of driving the protein expression of interleukin-1 receptor antagonist we demonstrated a decrease in lameness and decreased synovitis and osteoarthritis using gene therapy. Author’s address: Equine Orthopaedic Research Laboratory, Department of Clinical Sciences, Colorado State University, 300 West Drake, Fort Collins,...